RFC4 polyclonal, anti-human, rat
€388.00
In stock
SKU
BS7599
Background:
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Alternative Name:
A1 37, A1 37 kDa subunit, Activator 1 37, Activator 1 37 kDa subunit, Activator 1 subunit 4, Replication factor C 37, Replication factor C 37 kDa subunit, Replication factor C subunit 4, Replication factor C4, RF-C 37 kDa subunit, RFC 37, RFC37, RFC4 replication factor C (activator 1)4 37kDa, RfC4, RFC4_HUMAN,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100, IP: 1:50 - 1:200
Specificity: RFC4 polyclonal antibody detects endogenous levels of RFC4 protein.
Immunogen:
Recombinant full length Human RFC4.
MW: ~39 kDa
Swis Prot.: P35249
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Alternative Name:
A1 37, A1 37 kDa subunit, Activator 1 37, Activator 1 37 kDa subunit, Activator 1 subunit 4, Replication factor C 37, Replication factor C 37 kDa subunit, Replication factor C subunit 4, Replication factor C4, RF-C 37 kDa subunit, RFC 37, RFC37, RFC4 replication factor C (activator 1)4 37kDa, RfC4, RFC4_HUMAN,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100, IP: 1:50 - 1:200
Specificity: RFC4 polyclonal antibody detects endogenous levels of RFC4 protein.
Immunogen:
Recombinant full length Human RFC4.
MW: ~39 kDa
Swis Prot.: P35249
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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