RFRP-3 Peptide
€128.00
In stock
SKU
350591
Protein Family: Hormones
Pathway and Disease: Signaling Molecules and Interaction, Endocrine System, Nervous and Sensory Systems
Alternate Names: Pro-FMRFamide-related neuropeptide VF; FMRFamide-related peptide; Neuropeptide VF; NPVF; C7orf9; RFRP3; RFRP-3
Accession No.: Q9HCQ7
Description:
RFamide-related peptides (RFRP-1 and RFRP-3) belong to a group of RFamide peptides, which have an arginine-phenylalanine-amide structure at the C-term end. RFRPs share a similar C-term sequence with neuropeptide FF (NPFF) and have a relatively high affinity to GPR147 (also called NPFF1 receptor, RFRP receptor or OT7T022). RFRP-1 facilitates prolactin release from the pituitary and attenuates morphine-induced analgesia. RFRP-3 inhibits the gonadotrophin-releasing hormone neuron-luteinising hormone system in mammals and increases food intake. RFRP-1 and RFRP-3 are derived from the same preprotein (Pro-FMRFamide-related neuropeptide VF) and are co-expressed in single neurons in the dorsomedial hypothalamus, which plays a pivotal role in the control of stress responses in neuroendocrine, autonomic and behavioral systems. RFRP-3 inhibits forskolin-stimulated cAMP production in CHO cells expressing OT7T022 (ED50=0.7 nM).
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 969.1 g/mol
Sequence:
Human: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2 or H-VPNLPQRF-NH2
Composition:
C45H72N14O10
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Pathway and Disease: Signaling Molecules and Interaction, Endocrine System, Nervous and Sensory Systems
Alternate Names: Pro-FMRFamide-related neuropeptide VF; FMRFamide-related peptide; Neuropeptide VF; NPVF; C7orf9; RFRP3; RFRP-3
Accession No.: Q9HCQ7
Description:
RFamide-related peptides (RFRP-1 and RFRP-3) belong to a group of RFamide peptides, which have an arginine-phenylalanine-amide structure at the C-term end. RFRPs share a similar C-term sequence with neuropeptide FF (NPFF) and have a relatively high affinity to GPR147 (also called NPFF1 receptor, RFRP receptor or OT7T022). RFRP-1 facilitates prolactin release from the pituitary and attenuates morphine-induced analgesia. RFRP-3 inhibits the gonadotrophin-releasing hormone neuron-luteinising hormone system in mammals and increases food intake. RFRP-1 and RFRP-3 are derived from the same preprotein (Pro-FMRFamide-related neuropeptide VF) and are co-expressed in single neurons in the dorsomedial hypothalamus, which plays a pivotal role in the control of stress responses in neuroendocrine, autonomic and behavioral systems. RFRP-3 inhibits forskolin-stimulated cAMP production in CHO cells expressing OT7T022 (ED50=0.7 nM).
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 969.1 g/mol
Sequence:
Human: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2 or H-VPNLPQRF-NH2
Composition:
C45H72N14O10
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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