RFX3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5893
Background:
The EP element is bound by an ubiquitous nuclear protein complex that consists of homo- and heterodimers involving the RFX1, RFX2 and RFX3 proteins. The RFX proteins represent an essential class II transcription factor family that shares several conserved regions, including the centrally located DNA-binding domain (DBD) and the D region found in the C-terminal part of these proteins which facilitates dimerization. RFX complexes can activate the enhancer elements of several HBV genes and also promote the induction of MHC class II genes in response to interferon-g stimulation. Two additional subunits, RFX5, RFX-B/Ank, are also involved in the RFX complexes, yet they bind additional elements in the X1 half of the X box.
Alternative Name:
Transcription factor RFX3, Regulatory factor X 3
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RFX3 polyclonal antibody detects endogenous levels of RFX3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 694-739 of Human RFX3.
MW: ~ 83 kDa
Swis Prot.: P48380
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The EP element is bound by an ubiquitous nuclear protein complex that consists of homo- and heterodimers involving the RFX1, RFX2 and RFX3 proteins. The RFX proteins represent an essential class II transcription factor family that shares several conserved regions, including the centrally located DNA-binding domain (DBD) and the D region found in the C-terminal part of these proteins which facilitates dimerization. RFX complexes can activate the enhancer elements of several HBV genes and also promote the induction of MHC class II genes in response to interferon-g stimulation. Two additional subunits, RFX5, RFX-B/Ank, are also involved in the RFX complexes, yet they bind additional elements in the X1 half of the X box.
Alternative Name:
Transcription factor RFX3, Regulatory factor X 3
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RFX3 polyclonal antibody detects endogenous levels of RFX3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 694-739 of Human RFX3.
MW: ~ 83 kDa
Swis Prot.: P48380
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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