RFXANK Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP16143c
Background:
Major histocompatibility (MHC) class II molecules aretransmembrane proteins that have a central role in development andcontrol of the immune system. The protein encoded by this gene,along with regulatory factor X-associated protein and regulatoryfactor-5, forms a complex that binds to the X box motif of certainMHC class II gene promoters and activates their transcription. Oncebound to the promoter, this complex associates with thenon-DNA-binding factor MHC class II transactivator, which controlsthe cell type specificity and inducibility of MHC class II geneexpression. This protein contains ankyrin repeats involved inprotein-protein interactions. Mutations in this gene have beenlinked to bare lymphocyte syndrome type II, complementation groupB. Two transcript variants encoding different isoforms have beendescribed for this gene, with only one isoform showing activationactivity.
Other Names:
DNA-binding protein RFXANK, Ankyrin repeat family A protein 1, Regulatory factor X subunit B, RFX-B, Regulatory factor X-associated ankyrin-containing protein, RFXANK, ANKRA1, RFXB
Gene Name: RFXANK
Gene ID: 8625
Primary Accession: O14593
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Major histocompatibility (MHC) class II molecules aretransmembrane proteins that have a central role in development andcontrol of the immune system. The protein encoded by this gene,along with regulatory factor X-associated protein and regulatoryfactor-5, forms a complex that binds to the X box motif of certainMHC class II gene promoters and activates their transcription. Oncebound to the promoter, this complex associates with thenon-DNA-binding factor MHC class II transactivator, which controlsthe cell type specificity and inducibility of MHC class II geneexpression. This protein contains ankyrin repeats involved inprotein-protein interactions. Mutations in this gene have beenlinked to bare lymphocyte syndrome type II, complementation groupB. Two transcript variants encoding different isoforms have beendescribed for this gene, with only one isoform showing activationactivity.
Other Names:
DNA-binding protein RFXANK, Ankyrin repeat family A protein 1, Regulatory factor X subunit B, RFX-B, Regulatory factor X-associated ankyrin-containing protein, RFXANK, ANKRA1, RFXB
Gene Name: RFXANK
Gene ID: 8625
Primary Accession: O14593
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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