RGD-4C Peptide
€163.00
In stock
SKU
350363
Protein Family: CAM Ligands
Pathway and Disease: Cell Growth and Death
Alternate Names: Fibronectin; Arg-Gly-Asp; RGD; RGD-4C
Accession No.: P02751
Description:
The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD-4C is a double cyclic peptide that can bind preferentially to integrins at sites of tumor angiogenesis and inflamed synovium in vivo, and can be internalized into targeted cells. Recent applications include RGD-4C coupling to proapoptotic domains to treat tumors and inflammatory arthritis, or to radioactive labels for the broad spectrum imaging of tumor tissue.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 1145.29 g/mol
Sequence:
Sea Squirt: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH(Cys2-Cys10, Cys4-Cys8) or H-ACDCRGDCFCG-OH (Cys2-Cys10, Cys4-Cys8)
Composition:
C42H60N14O16S4
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Pathway and Disease: Cell Growth and Death
Alternate Names: Fibronectin; Arg-Gly-Asp; RGD; RGD-4C
Accession No.: P02751
Description:
The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD-4C is a double cyclic peptide that can bind preferentially to integrins at sites of tumor angiogenesis and inflamed synovium in vivo, and can be internalized into targeted cells. Recent applications include RGD-4C coupling to proapoptotic domains to treat tumors and inflammatory arthritis, or to radioactive labels for the broad spectrum imaging of tumor tissue.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 1145.29 g/mol
Sequence:
Sea Squirt: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH(Cys2-Cys10, Cys4-Cys8) or H-ACDCRGDCFCG-OH (Cys2-Cys10, Cys4-Cys8)
Composition:
C42H60N14O16S4
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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