RGD Peptide
€240.00
In stock
SKU
350362
Protein Family: CAM Ligands
Pathway and Disease: Cell Growth and Death
Alternate Names: Fibronectin; Arg-Gly-Asp; RGD
Accession No.: P02751
Description:
The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD peptide acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering. Research demonstrates that RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. The RGD peptide can serve as a cell adhesion site of extracellular matrix, cell surface proteins, and integrins. In addition, RGD peptide can inhibit ACK-2 activation through cell adhesion.
Format:
Each vial contains 5 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 346.3 g/mol
Sequence:
H-Arg-Gly-Asp-OH or H-RGD-OH
Composition:
C12H22N6O6
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Pathway and Disease: Cell Growth and Death
Alternate Names: Fibronectin; Arg-Gly-Asp; RGD
Accession No.: P02751
Description:
The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD peptide acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering. Research demonstrates that RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. The RGD peptide can serve as a cell adhesion site of extracellular matrix, cell surface proteins, and integrins. In addition, RGD peptide can inhibit ACK-2 activation through cell adhesion.
Format:
Each vial contains 5 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 346.3 g/mol
Sequence:
H-Arg-Gly-Asp-OH or H-RGD-OH
Composition:
C12H22N6O6
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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