RGS14 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71387
Background:
RGS domains bind directly to activated Ga subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Ga-GTP and Gbg. RGS proteins shorten the lifetime of the activated G protein. Western blot analysis shows strong expression of RGS14 as a primarily cytosolic protein restricted to brain and spleen. It is suggested that RGS14 may constitute a bridging molecule that allows cross-regulation of signaling pathways downstream from G protein-coupled receptors.
Alternative Name:
Regulator of G-protein signaling 14
Application Dilution: WB: 1:500 - 1:2000
Specificity: RGS14 polyclonal antibody detects endogenous levels of RGS14 protein.
Immunogen:
Recombinant protein of human RGS14.
MW: ~ 61 kDa
Swis Prot.: O43566
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RGS domains bind directly to activated Ga subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Ga-GTP and Gbg. RGS proteins shorten the lifetime of the activated G protein. Western blot analysis shows strong expression of RGS14 as a primarily cytosolic protein restricted to brain and spleen. It is suggested that RGS14 may constitute a bridging molecule that allows cross-regulation of signaling pathways downstream from G protein-coupled receptors.
Alternative Name:
Regulator of G-protein signaling 14
Application Dilution: WB: 1:500 - 1:2000
Specificity: RGS14 polyclonal antibody detects endogenous levels of RGS14 protein.
Immunogen:
Recombinant protein of human RGS14.
MW: ~ 61 kDa
Swis Prot.: O43566
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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