RHCE Antibody (C-term) Blocking Peptide

Background:
The Rh blood group system is the second most clinicallysignificant of the blood groups, second only to ABO. It is also themost polymorphic of the blood groups, with variations due todeletions, gene conversions, and missense mutations. The Rh bloodgroup includes this gene which encodes both the RhC and RhEantigens on a single polypeptide and a second gene which encodesthe RhD protein. The classification of Rh-positive and Rh-negativeindividuals is determined by the presence or absence of the highlyimmunogenic RhD protein on the surface of erythrocytes. A mutationin this gene results in amorph-type Rh-null disease. Alternativesplicing of this gene results in four transcript variants encodingfour different isoforms.
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.