RHOBTB3 (L365) polyclonal, anti-human, rat
€305.00
In stock
SKU
BS9159
Background:
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues.
Alternative Name:
KIAA0878, Rho related BTB domain containing protein 3, RHOBTB 3,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RHOBTB3 (L365) polyclonal antibody detects endogenous levels of RHOBTB3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 341-390 of Human RHOBTB3.
MW: ~ 69 kDa
Swis Prot.: O94955
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues.
Alternative Name:
KIAA0878, Rho related BTB domain containing protein 3, RHOBTB 3,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RHOBTB3 (L365) polyclonal antibody detects endogenous levels of RHOBTB3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 341-390 of Human RHOBTB3.
MW: ~ 69 kDa
Swis Prot.: O94955
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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