RHOC Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14105b
Background:
This gene encodes a member of the Rho family of smallGTPases, which cycle between inactive GDP-bound and activeGTP-bound states and function as molecular switches in signaltransduction cascades. Rho proteins promote reorganization of theactin cytoskeleton and regulate cell shape, attachment, andmotility. The protein encoded by this gene is prenylated at itsC-terminus, and localizes to the cytoplasm and plasma membrane. Itis thought to be important in cell locomotion. Overexpression ofthis gene is associated with tumor cell proliferation andmetastasis. Multiple alternatively spliced variants, encoding thesame protein, have been identified.
Other Names:
Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, h9, RHOC, ARH9, ARHC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14105b was selected from the C-term region of RHOC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RHOC
Gene ID: 389
Primary Accession: P08134
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the Rho family of smallGTPases, which cycle between inactive GDP-bound and activeGTP-bound states and function as molecular switches in signaltransduction cascades. Rho proteins promote reorganization of theactin cytoskeleton and regulate cell shape, attachment, andmotility. The protein encoded by this gene is prenylated at itsC-terminus, and localizes to the cytoplasm and plasma membrane. Itis thought to be important in cell locomotion. Overexpression ofthis gene is associated with tumor cell proliferation andmetastasis. Multiple alternatively spliced variants, encoding thesame protein, have been identified.
Other Names:
Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, h9, RHOC, ARH9, ARHC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14105b was selected from the C-term region of RHOC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RHOC
Gene ID: 389
Primary Accession: P08134
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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