RHOC antibody (clone 2.0E+12), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT3636a
Catalog Number: AC-AT3636a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT3636a-RHOC-Antibody-monoclonal-M01">Request Information AC-AT3636a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT3636a-RHOC-Antibody-monoclonal-M01">Request Information AC-AT3636a">Request Information
Background:
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Other Names:
Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, h9, RHOC, ARH9, ARHC
Antigen Type:
Recombinant Protein
Gene Name: RHOC
Gene ID: 389
NCBI Accession: NP_001036143.1;NP_001036144.1;NP_786886.1
Primary Accession: P08134
Other Accession: BC007245
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Other Names:
Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, h9, RHOC, ARH9, ARHC
Antigen Type:
Recombinant Protein
Gene Name: RHOC
Gene ID: 389
NCBI Accession: NP_001036143.1;NP_001036144.1;NP_786886.1
Primary Accession: P08134
Other Accession: BC007245
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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