RIMS2 Antibody (S427) Blocking Peptide
€363.00
In stock
SKU
AC-BP7597d
Background:
RIMS2 is a Rab effector involved in exocytosis. It may act as a scaffold protein. The mature cytomatrix at the active zone (CAZ) of the synapse is defined by a set of multidomain proteins that harbor several protein??rotein or protein??ipid interaction domains. The complete protein composition of the CAZ is not known to date, but it includes the proteins RIMs, Munc13-1, ERC/CAST, Piccolo/Aczonin and Bassoon. RIMs are presynaptic active zone proteins that regulate Ca2+ triggered release of neurotransmitters.
Other Names:
Regulating synaptic membrane exocytosis protein 2, Rab-3-interacting molecule 2, RIM 2, Rab-3-interacting protein 3, RIMS2, KIAA0751, RAB3IP3, RIM2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7597d was selected from the S427 region of human RIMS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RIMS2
Gene ID: 9699
Primary Accession: Q9UQ26
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
RIMS2 is a Rab effector involved in exocytosis. It may act as a scaffold protein. The mature cytomatrix at the active zone (CAZ) of the synapse is defined by a set of multidomain proteins that harbor several protein??rotein or protein??ipid interaction domains. The complete protein composition of the CAZ is not known to date, but it includes the proteins RIMs, Munc13-1, ERC/CAST, Piccolo/Aczonin and Bassoon. RIMs are presynaptic active zone proteins that regulate Ca2+ triggered release of neurotransmitters.
Other Names:
Regulating synaptic membrane exocytosis protein 2, Rab-3-interacting molecule 2, RIM 2, Rab-3-interacting protein 3, RIMS2, KIAA0751, RAB3IP3, RIM2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7597d was selected from the S427 region of human RIMS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RIMS2
Gene ID: 9699
Primary Accession: Q9UQ26
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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