RLN1/RLN2 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13864b
Background:
Relaxins are known endocrine and autocrine/paracrinehormones, belonging to the insulin gene superfamily. In the humanthere are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.RLN1 and RLN2 share high sequence homology. This encoded protein issynthesized as a single-chain polypeptide but the active formconsists of an A chain and a B chain linked by disulfide bonds;however, their exact cleavage sites have not been described.Relaxin is produced by the ovary, and targets the mammalianreproductive system to ripen the cervix, elongate the pubicsymphysis and inhibit uterine contraction. It may have additionalroles in enhancing sperm motility, regulating blood pressure,controlling heart rate and releasing oxytocin and vasopressin. Thisgene has multiple polyadenylation sites. There are multiplealternatively spliced transcript variants described for this genebut their full length nature is not known yet. [provided byRefSeq].
Other Names:
Prorelaxin H1, Relaxin B chain, Relaxin A chain, RLN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13864b was selected from the C-term region of RLN1/RLN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RLN1
Gene ID: 6013
Primary Accession: P04808
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Relaxins are known endocrine and autocrine/paracrinehormones, belonging to the insulin gene superfamily. In the humanthere are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.RLN1 and RLN2 share high sequence homology. This encoded protein issynthesized as a single-chain polypeptide but the active formconsists of an A chain and a B chain linked by disulfide bonds;however, their exact cleavage sites have not been described.Relaxin is produced by the ovary, and targets the mammalianreproductive system to ripen the cervix, elongate the pubicsymphysis and inhibit uterine contraction. It may have additionalroles in enhancing sperm motility, regulating blood pressure,controlling heart rate and releasing oxytocin and vasopressin. Thisgene has multiple polyadenylation sites. There are multiplealternatively spliced transcript variants described for this genebut their full length nature is not known yet. [provided byRefSeq].
Other Names:
Prorelaxin H1, Relaxin B chain, Relaxin A chain, RLN1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13864b was selected from the C-term region of RLN1/RLN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RLN1
Gene ID: 6013
Primary Accession: P04808
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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