RNASE1 polyclonal, anti-human, mouse

RNASE1 polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS7958
Catalog Number: BS7958
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
RNase1 (ribonuclease, RNase A family, 1 (pancreatic), Rib1) gene encodes a 156 amino acid member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. RNase 1 endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. RNase 1 prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. RNase 1 is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. RNase1 is a digestive enzyme that has been recognized to be one of the most attractive model systems for molecular evolutionary studies. The RNase1 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 14q11.2, where it is linked to seven other RNase A superfamily genes. The entire RNase A cluster spans 368 kb.

Alternative Name:
HP-RNase, Pancreatic ribonuclease, Rib 1, RIB-1, Rib1, Ribonuclease 1, Ribonuclease A, Ribonuclease a family 1, Ribonuclease pancreatic, Ribonuclease RNase A family 1, Ribonuclease RNase A family 1 pancreatic, RNAS1_HUMAN, RNase 1, RNase A, RNase UpI-1, Rnase1, RNAseA,

Application Dilution: WB: 1:500 - 1:2000

Specificity: RNASE1 polyclonal antibody detects endogenous levels of RNASE1 protein.

Immunogen:
Recombinant full length Human RNASE1.

MW: ~ 18 kDa

Swis Prot.: P07998

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
More Information
Is Featured? No
Write Your Own Review
You're reviewing:RNASE1 polyclonal, anti-human, mouse