RNF139 antibody (clone 3D10), anti-human
€435.00
In stock
SKU
AC-AT3665a
Catalog Number: AC-AT3665a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
Request Information AC-AT3665a">Request Information
Background:
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Other Names:
E3 ubiquitin-protein ligase RNF139, 632-, RING finger protein 139, Translocation in renal carcinoma on chromosome 8 protein, RNF139 (HGNC:17023)
Antigen Type:
Recombinant Protein
Gene Name: RNF139 (HGNC:17023)
Gene ID: 11236
NCBI Accession: NP_009149.2
Primary Accession: Q8WU17
Other Accession: NM_007218
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Other Names:
E3 ubiquitin-protein ligase RNF139, 632-, RING finger protein 139, Translocation in renal carcinoma on chromosome 8 protein, RNF139 (HGNC:17023)
Antigen Type:
Recombinant Protein
Gene Name: RNF139 (HGNC:17023)
Gene ID: 11236
NCBI Accession: NP_009149.2
Primary Accession: Q8WU17
Other Accession: NM_007218
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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