RNF14 antibody (clone 4G9), anti-human
€435.00
In stock
SKU
AC-AT3666a
Catalog Number: AC-AT3666a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT3666a">Request Information
Background:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Other Names:
E3 ubiquitin-protein ligase RNF14, 632-, Androgen receptor-associated protein 54, HFB30, RING finger protein 14, Triad2 protein, RNF14, ARA54
Antigen Type:
Recombinant Protein
Gene Name: RNF14 {ECO:0000303|PubMed:36638793, ECO:0000312|HGNC:HGNC:10058}
Gene ID: 9604
NCBI Accession: NP_001188294.1;NP_004281.1;NP_899645.1;NP_899646.1;NP_899647.1;NP_899648.1
Primary Accession: Q9UBS8
Other Accession: NM_004290
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Other Names:
E3 ubiquitin-protein ligase RNF14, 632-, Androgen receptor-associated protein 54, HFB30, RING finger protein 14, Triad2 protein, RNF14, ARA54
Antigen Type:
Recombinant Protein
Gene Name: RNF14 {ECO:0000303|PubMed:36638793, ECO:0000312|HGNC:HGNC:10058}
Gene ID: 9604
NCBI Accession: NP_001188294.1;NP_004281.1;NP_899645.1;NP_899646.1;NP_899647.1;NP_899648.1
Primary Accession: Q9UBS8
Other Accession: NM_004290
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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