RNF166 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71145
Background:
RNF166 (RING finger protein 166) is a 237 amino acid protein that contains one RING-type zinc finger and a UIM (ubiquitin-interacting motif) repeat. Existing as two alternatively spliced isoforms, RNF166 is encoded by a gene that maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Alternative Name:
RING finger protein 166
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: RNF166 polyclonal antibody detects endogenous levels of RNF166 protein.
Immunogen:
A synthetic peptide of human RNF166.
MW: ~ 26 kDa
Swis Prot.: Q96A37
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RNF166 (RING finger protein 166) is a 237 amino acid protein that contains one RING-type zinc finger and a UIM (ubiquitin-interacting motif) repeat. Existing as two alternatively spliced isoforms, RNF166 is encoded by a gene that maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Alternative Name:
RING finger protein 166
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: RNF166 polyclonal antibody detects endogenous levels of RNF166 protein.
Immunogen:
A synthetic peptide of human RNF166.
MW: ~ 26 kDa
Swis Prot.: Q96A37
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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