RNF8 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8825
Background:
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
Alternative Name:
E3 ubiquitin-protein ligase RNF8, hRNF8, RING finger protein 8, RNF8, KIAA0646
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: RNF8 polyclonal antibody detects endogenous levels of RNF8 protein.
Immunogen:
Recombinant full length Human RNF8.
MW: ~ 56kDa
Swis Prot.: O76064
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
Alternative Name:
E3 ubiquitin-protein ligase RNF8, hRNF8, RING finger protein 8, RNF8, KIAA0646
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: RNF8 polyclonal antibody detects endogenous levels of RNF8 protein.
Immunogen:
Recombinant full length Human RNF8.
MW: ~ 56kDa
Swis Prot.: O76064
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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