Rock-2 polyclonal, anti-human, mouse, rat

Rock-2 polyclonal, anti-human, mouse, rat

€388.00
In stock
SKU
BS7216
Catalog Number: BS7216
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IHC, IF

Datasheet
Background:
Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been de-scribed, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka) for Rho-associated coil-containing protein kinase. Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase.

Alternative Name:
Rho-associated protein kinase 2, EC=2.7.11.1, Alternative name(s):, Rho kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, Rho-associated, coiled-coil-containing protein kinase II, ROCK-II, p164 ROCK-2, ROCK2, KIAA0619

Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200

Specificity: Rock-2 polyclonal antibody detects endogenous levels of Rock-2 protein.

Immunogen:
Recombinant full length Human Rock-2.

MW: ~ 160 kDa

Swis Prot.: O75116

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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