RPA1 polyclonal, anti-human
€388.00
In stock
SKU
BS6094
Background:
Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Alternative Name:
Dmrpa1, Drosophila Replication Protein A, DRPA, HSSB, Human single stranded DNA binding protein, MST075, MSTP075, p70, REPA1, Replication factor A, Replication factor A protein 1, Replication protein A 70 a DNA-binding subunit, Replication protein A 70 a DNA binding subunit, Replication protein A1 70 a, Replication protein A1, RF A, RF-A protein 1, RFA, RFA1, RP A, RP-A p70, RPA 70, RPA, RPA1, Single stranded binding protein 70, Single-stranded DNA-binding protein
Application Dilution: WB: 1:500 - 1:2000
Specificity: RPA1 polyclonal antibody detects endogenous levels of RPA1 protein.
Immunogen:
Recombinant full length Human RPA1.
MW: ~ 68 kDa
Swis Prot.: P27694
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Alternative Name:
Dmrpa1, Drosophila Replication Protein A, DRPA, HSSB, Human single stranded DNA binding protein, MST075, MSTP075, p70, REPA1, Replication factor A, Replication factor A protein 1, Replication protein A 70 a DNA-binding subunit, Replication protein A 70 a DNA binding subunit, Replication protein A1 70 a, Replication protein A1, RF A, RF-A protein 1, RFA, RFA1, RP A, RP-A p70, RPA 70, RPA, RPA1, Single stranded binding protein 70, Single-stranded DNA-binding protein
Application Dilution: WB: 1:500 - 1:2000
Specificity: RPA1 polyclonal antibody detects endogenous levels of RPA1 protein.
Immunogen:
Recombinant full length Human RPA1.
MW: ~ 68 kDa
Swis Prot.: P27694
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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