RPA70 (clone 8C3-D12-H10), anti-human, mouse, rat, primate antibody
€295.00
In stock
SKU
AC-ABV12048-100
Catalog Number: AC-ABV12048-100
Size: 100 µg
Host: Mouse IgG
Applications: WB, IF, IP
Datasheet
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Size: 100 µg
Host: Mouse IgG
Applications: WB, IF, IP
Datasheet
Request Information
Background:
Replication protein A 70 kDa DNA-binding subunit plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage.
Other Names:
Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1, Single-stranded DNA-binding protein, RPA1
Primary Accession: P27694
Gene Name: RPA1
Gene ID: 6117
Replication protein A 70 kDa DNA-binding subunit plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage.
Other Names:
Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1, Single-stranded DNA-binding protein, RPA1
Primary Accession: P27694
Gene Name: RPA1
Gene ID: 6117
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