RPGR polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7115
Background:
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
Alternative Name:
X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3, CRD, COD1, PCDX, RP15, orf15, CORDX1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: RPGR polyclonal antibody detects endogenous levels of RPGR protein.
Immunogen:
Recombinant full length Human RPGR.
MW: ~ 70, 83, 90, 113, 127 kDa
Swis Prot.: Q92834
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
Alternative Name:
X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3, CRD, COD1, PCDX, RP15, orf15, CORDX1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: RPGR polyclonal antibody detects endogenous levels of RPGR protein.
Immunogen:
Recombinant full length Human RPGR.
MW: ~ 70, 83, 90, 113, 127 kDa
Swis Prot.: Q92834
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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