BRMS-1 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73341
Background:
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Other Names:
BRMS1; Breast cancer metastasis-suppressor 1
Antigen Type: synthetic peptide
Antigen Type: BRMS1
Gene ID: 25855
Primary Accession: Q9HCU9
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Other Names:
BRMS1; Breast cancer metastasis-suppressor 1
Antigen Type: synthetic peptide
Antigen Type: BRMS1
Gene ID: 25855
Primary Accession: Q9HCU9
| Is Featured? | No |
|---|
Write Your Own Review