RPL28 (Y77) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3790
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alternative Name:
RPL 28, 60S ribosomal protein L28,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200, IP: 1:10~1:100
Specificity: Ribosomal Protein L28 (Y77) polyclonal antibody detects endogenous levels of Ribosomal Protein L28 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 50-100 of Human Ribosomal Protein L28.
MW: ~ 16 kDa
Swis Prot.: P46779
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alternative Name:
RPL 28, 60S ribosomal protein L28,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200, IP: 1:10~1:100
Specificity: Ribosomal Protein L28 (Y77) polyclonal antibody detects endogenous levels of Ribosomal Protein L28 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 50-100 of Human Ribosomal Protein L28.
MW: ~ 16 kDa
Swis Prot.: P46779
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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