RPL3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5904
Background:
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L3, also known as RPL3 or TARBP-B, is a 403 amino acid protein that localizes to the cytoplasm and belongs to the L3P family of ribosomal proteins. Expressed as multiple alternatively spliced isoforms, Ribosomal Protein L3 is able to bind to HIV-1 mRNA, possibly activating HIV-1 protein translation. Like most ribosomal proteins, Ribosomal Protein L3 exists as multiple processed pseudogenes that are scattered throughout the genome.
Alternative Name:
60S ribosomal protein L3, HIV-1 TAR RNA-binding protein B, TARBP-B, OK/SW-cl.32
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RPL3 polyclonal antibody detects endogenous levels of RPL3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 262-307 of Human RPL3.
MW: ~ 46 kDa
Swis Prot.: P39023
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L3, also known as RPL3 or TARBP-B, is a 403 amino acid protein that localizes to the cytoplasm and belongs to the L3P family of ribosomal proteins. Expressed as multiple alternatively spliced isoforms, Ribosomal Protein L3 is able to bind to HIV-1 mRNA, possibly activating HIV-1 protein translation. Like most ribosomal proteins, Ribosomal Protein L3 exists as multiple processed pseudogenes that are scattered throughout the genome.
Alternative Name:
60S ribosomal protein L3, HIV-1 TAR RNA-binding protein B, TARBP-B, OK/SW-cl.32
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RPL3 polyclonal antibody detects endogenous levels of RPL3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 262-307 of Human RPL3.
MW: ~ 46 kDa
Swis Prot.: P39023
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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