RPL7 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16047a
Background:
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L30P family of ribosomal proteins. It contains an N-terminalbasic region-leucine zipper (BZIP)-like domain and the RNPconsensus submotif RNP2. In vitro the BZIP-like domain mediateshomodimerization and stable binding to DNA and RNA, with apreference for 28S rRNA and mRNA. The protein can inhibit cell-freetranslation of mRNAs, suggesting that it plays a regulatory role inthe translation apparatus. It is located in the cytoplasm. Theprotein has been shown to be an autoantigen in patients withsystemic autoimmune diseases, such as systemic lupus erythematosus.As is typical for genes encoding ribosomal proteins, there aremultiple processed pseudogenes of this gene dispersed through thegenome.
Other Names:
60S ribosomal protein L7, RPL7
Gene Name: RPL7
Gene ID: 6129
Primary Accession: P18124
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 60S subunit. The protein belongsto the L30P family of ribosomal proteins. It contains an N-terminalbasic region-leucine zipper (BZIP)-like domain and the RNPconsensus submotif RNP2. In vitro the BZIP-like domain mediateshomodimerization and stable binding to DNA and RNA, with apreference for 28S rRNA and mRNA. The protein can inhibit cell-freetranslation of mRNAs, suggesting that it plays a regulatory role inthe translation apparatus. It is located in the cytoplasm. Theprotein has been shown to be an autoantigen in patients withsystemic autoimmune diseases, such as systemic lupus erythematosus.As is typical for genes encoding ribosomal proteins, there aremultiple processed pseudogenes of this gene dispersed through thegenome.
Other Names:
60S ribosomal protein L7, RPL7
Gene Name: RPL7
Gene ID: 6129
Primary Accession: P18124
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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