RPS19 antibody (clone 3C6), anti-human
€435.00
In stock
SKU
AC-AT3713a
Catalog Number: AC-AT3713a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB
Request Information AC-AT3713a">Request Information
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Other Names:
40S ribosomal protein S19, RPS19
Antigen Type:
Recombinant Protein
Gene Name: RPS19 (HGNC:10402)
Gene ID: 6223
NCBI Accession: NP_001013.1
Primary Accession: P39019
Other Accession: BC000023
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Other Names:
40S ribosomal protein S19, RPS19
Antigen Type:
Recombinant Protein
Gene Name: RPS19 (HGNC:10402)
Gene ID: 6223
NCBI Accession: NP_001013.1
Primary Accession: P39019
Other Accession: BC000023
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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