RPS3 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12605b
Background:
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 40S subunit, where it forms partof the domain where translation is initiated. The protein belongsto the S3P family of ribosomal proteins. Studies of the mouse andrat proteins have demonstrated that the protein has anextraribosomal role as an endonuclease involved in the repair ofUV-induced DNA damage. The protein appears to be located in boththe cytoplasm and nucleus but not in the nucleolus. Higher levelsof expression of this gene in colon adenocarcinomas and adenomatouspolyps compared to adjacent normal colonic mucosa have beenobserved. This gene is co-transcribed with the small nucleolar RNAgenes U15A and U15B, which are located in its first and fifthintrons, respectively. As is typical for genes encoding ribosomalproteins, there are multiple processed pseudogenes of this genedispersed through the genome.
Other Names:
40S ribosomal protein S3, RPS3
Gene Name: RPS3 {ECO:0000303|PubMed:11875025}
Gene ID: 6188
Primary Accession: P23396
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 40S subunit, where it forms partof the domain where translation is initiated. The protein belongsto the S3P family of ribosomal proteins. Studies of the mouse andrat proteins have demonstrated that the protein has anextraribosomal role as an endonuclease involved in the repair ofUV-induced DNA damage. The protein appears to be located in boththe cytoplasm and nucleus but not in the nucleolus. Higher levelsof expression of this gene in colon adenocarcinomas and adenomatouspolyps compared to adjacent normal colonic mucosa have beenobserved. This gene is co-transcribed with the small nucleolar RNAgenes U15A and U15B, which are located in its first and fifthintrons, respectively. As is typical for genes encoding ribosomalproteins, there are multiple processed pseudogenes of this genedispersed through the genome.
Other Names:
40S ribosomal protein S3, RPS3
Gene Name: RPS3 {ECO:0000303|PubMed:11875025}
Gene ID: 6188
Primary Accession: P23396
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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