RPS3 antibody (clone 2A8), anti-human
€435.00
In stock
SKU
AC-AT3717a
Catalog Number: AC-AT3717a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT3717a">Request Information
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Other Names:
40S ribosomal protein S3, RPS3
Antigen Type:
Recombinant Protein
Gene Name: RPS3 {ECO:0000303|PubMed:11875025}
Gene ID: 6188
NCBI Accession: NP_000996.2;NP_001243731.1;NP_001247435.1;NP_001247436.1
Primary Accession: P23396
Other Accession: NM_001005
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Other Names:
40S ribosomal protein S3, RPS3
Antigen Type:
Recombinant Protein
Gene Name: RPS3 {ECO:0000303|PubMed:11875025}
Gene ID: 6188
NCBI Accession: NP_000996.2;NP_001243731.1;NP_001247435.1;NP_001247436.1
Primary Accession: P23396
Other Accession: NM_001005
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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