RPS6 Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP20175a
Background:
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a cytoplasmicribosomal protein that is a component of the 40S subunit. Theprotein belongs to the S6E family of ribosomal proteins. It is themajor substrate of protein kinases in the ribosome, with subsets offive C-terminal serine residues phosphorylated by different proteinkinases. Phosphorylation is induced by a wide range of stimuli,including growth factors, tumor-promoting agents, and mitogens.Dephosphorylation occurs at growth arrest. The protein maycontribute to the control of cell growth and proliferation throughthe selective translation of particular classes of mRNA. As istypical for genes encoding ribosomal proteins, there are multipleprocessed pseudogenes of this gene dispersed through the genome.
Other Names:
40S ribosomal protein S6, Phosphoprotein NP33, RPS6
Target/Specificity:
The synthetic peptide sequence is selected from aa 14-27 of HUMAN RPS6
Gene Name: RPS6 {ECO:0000303|PubMed:29563586, ECO:0000312|HGNC:HGNC:10429}
Gene ID: 6194
Primary Accession: P62753
Other Accession: P62755; P62754; Q4R4K6; Q5E995; NP_001001.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a cytoplasmicribosomal protein that is a component of the 40S subunit. Theprotein belongs to the S6E family of ribosomal proteins. It is themajor substrate of protein kinases in the ribosome, with subsets offive C-terminal serine residues phosphorylated by different proteinkinases. Phosphorylation is induced by a wide range of stimuli,including growth factors, tumor-promoting agents, and mitogens.Dephosphorylation occurs at growth arrest. The protein maycontribute to the control of cell growth and proliferation throughthe selective translation of particular classes of mRNA. As istypical for genes encoding ribosomal proteins, there are multipleprocessed pseudogenes of this gene dispersed through the genome.
Other Names:
40S ribosomal protein S6, Phosphoprotein NP33, RPS6
Target/Specificity:
The synthetic peptide sequence is selected from aa 14-27 of HUMAN RPS6
Gene Name: RPS6 {ECO:0000303|PubMed:29563586, ECO:0000312|HGNC:HGNC:10429}
Gene ID: 6194
Primary Accession: P62753
Other Accession: P62755; P62754; Q4R4K6; Q5E995; NP_001001.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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