RPS6KA3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7774
Background:
The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. The family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase β, which are thought to have similar regulatory functions. MSK1 (also designated RLPK) is a novel Rsk-related protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.
Alternative Name:
90 kDa ribosomal protein S6 kinase 3, CLS, HU 3, HU2, HU3, Insulin stimulated protein kinase 1, Insulin-stimulated protein kinase 1, ISPK-1, ISPK1, KS6A3_HUMAN, MAP kinase activated protein kinase 1b, MAP kinase-activated protein kinase 1b, MAPK activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK 1b, MAPKAPK-1b, MAPKAPK1B, Mental retardation, X linked 19, MRX19, OTTHUMP00000023036, p90 RSK2, p90 RSK3, p90-RSK 3, p90RSK3, pp90RSK2, Ribosomal protein S6 kinase 90kDa polypeptide 3, Ribosomal protein S6 kinase alpha 3, Ribosomal protein S6 kinase alpha-3, Ribosomal protein s6 kinase ii alpha 2, Ribosomal S6 kinase 2, Rps6ka3, RSK, RSK-2, RSK2, S6 kinase 2, S6K alpha3, S6K-alpha-3,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: RPS6KA3 polyclonal antibody detects endogenous levels of RPS6KA3 protein.
Immunogen:
Recombinant full length Human RPS6KA3.
MW: ~ 84 kDa
Swis Prot.: P51812
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. The family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase β, which are thought to have similar regulatory functions. MSK1 (also designated RLPK) is a novel Rsk-related protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.
Alternative Name:
90 kDa ribosomal protein S6 kinase 3, CLS, HU 3, HU2, HU3, Insulin stimulated protein kinase 1, Insulin-stimulated protein kinase 1, ISPK-1, ISPK1, KS6A3_HUMAN, MAP kinase activated protein kinase 1b, MAP kinase-activated protein kinase 1b, MAPK activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK 1b, MAPKAPK-1b, MAPKAPK1B, Mental retardation, X linked 19, MRX19, OTTHUMP00000023036, p90 RSK2, p90 RSK3, p90-RSK 3, p90RSK3, pp90RSK2, Ribosomal protein S6 kinase 90kDa polypeptide 3, Ribosomal protein S6 kinase alpha 3, Ribosomal protein S6 kinase alpha-3, Ribosomal protein s6 kinase ii alpha 2, Ribosomal S6 kinase 2, Rps6ka3, RSK, RSK-2, RSK2, S6 kinase 2, S6K alpha3, S6K-alpha-3,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: RPS6KA3 polyclonal antibody detects endogenous levels of RPS6KA3 protein.
Immunogen:
Recombinant full length Human RPS6KA3.
MW: ~ 84 kDa
Swis Prot.: P51812
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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