RPS6KB1 antibody (clone 10000000000), anti-human
€435.00
In stock
SKU
AC-AT3722a
Catalog Number: AC-AT3722a
Size: 100 µg
Isotype: mouse IgG IgA IgM Mix
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG IgA IgM Mix
Applications: WB, IF, E
Request Information AC-AT3722a">Request Information
Background:
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
Other Names:
Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, RPS6KB1, STK14A
Antigen Type:
Recombinant Protein
Gene Name: RPS6KB1
Gene ID: 6198
NCBI Accession: NP_001258989.1;NP_003152.1
Primary Accession: P23443
Other Accession: NM_003161
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
Other Names:
Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, RPS6KB1, STK14A
Antigen Type:
Recombinant Protein
Gene Name: RPS6KB1
Gene ID: 6198
NCBI Accession: NP_001258989.1;NP_003152.1
Primary Accession: P23443
Other Accession: NM_003161
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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