RPTOR (clone 5A3A4), anti-human

Background:
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cell biology, Epigenetics and nuclear signaling, Signal transduction

Synonyms: KOG1, Mip1

Immunogen: Purified recombinant fragment of human RPTOR (AA: 874-1009) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage