RRBP1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71683
Background:
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
Alternative Name:
Ribosome-binding protein 1, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398
Application Dilution: WB : 1:500 - 1:2000
Specificity: RRBP1 polyclonal antibody detects endogenous levels of RRBP1 protein.
Immunogen:
Recombinant protein of human RRBP1
MW: Predicted band size: 152 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9P2E9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
Alternative Name:
Ribosome-binding protein 1, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398
Application Dilution: WB : 1:500 - 1:2000
Specificity: RRBP1 polyclonal antibody detects endogenous levels of RRBP1 protein.
Immunogen:
Recombinant protein of human RRBP1
MW: Predicted band size: 152 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9P2E9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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