RREB1 (E597) polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS9158
Background:
RREB1 (Ras responsive element binding protein 1), also known as FINB, LZ321 or Zep-1, is a 1,687 amino acid protein that localizes to nuclear speckles and contains fifteen C2H2-type zinc fingers. Expressed in pancreas, heart, liver, placenta, lung, kidney and skeletal muscle, RREB1 functions as a transcription factor that binds to the Ras-responsive element (RRE) of target gene promotors, thereby inducing their transcription. In addition, RREB1 is thought to be involved in Raf/Ras-mediated cell differentiation, possibly by enhancing the expression of Calcitonin, a hormone that is produced by the thyroid gland and plays an essential role in maintaining blood calcium levels. Due to its involvement in cell differentiation events, RREB1 may be involved in Raf/Rasrelated tumor formation. Four isoforms of RREB1 exist due to alternative splicing.
Alternative Name:
FINB, Finger protein in nuclear bodies, Hindsight homolog, HNT, LZ321, Raf responsive zinc finger protein LZ321, Raf-responsive zinc finger protein LZ321, RAS responsive element binding protein 1, Ras-responsive element-binding protein 1, RREB 1, RREB-1, Rreb1, RREB1, Zep 1, Zep-1, Zep1, Zinc finger motif enhancer binding protein 1, Zinc finger motif enhancer-binding protein 1,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RREB1 (E597) polyclonal antibody detects endogenous levels of RREB1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 560-610 of Human RREB1.
MW: ~ 181 kDa
Swis Prot.: Q92766
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RREB1 (Ras responsive element binding protein 1), also known as FINB, LZ321 or Zep-1, is a 1,687 amino acid protein that localizes to nuclear speckles and contains fifteen C2H2-type zinc fingers. Expressed in pancreas, heart, liver, placenta, lung, kidney and skeletal muscle, RREB1 functions as a transcription factor that binds to the Ras-responsive element (RRE) of target gene promotors, thereby inducing their transcription. In addition, RREB1 is thought to be involved in Raf/Ras-mediated cell differentiation, possibly by enhancing the expression of Calcitonin, a hormone that is produced by the thyroid gland and plays an essential role in maintaining blood calcium levels. Due to its involvement in cell differentiation events, RREB1 may be involved in Raf/Rasrelated tumor formation. Four isoforms of RREB1 exist due to alternative splicing.
Alternative Name:
FINB, Finger protein in nuclear bodies, Hindsight homolog, HNT, LZ321, Raf responsive zinc finger protein LZ321, Raf-responsive zinc finger protein LZ321, RAS responsive element binding protein 1, Ras-responsive element-binding protein 1, RREB 1, RREB-1, Rreb1, RREB1, Zep 1, Zep-1, Zep1, Zinc finger motif enhancer binding protein 1, Zinc finger motif enhancer-binding protein 1,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: RREB1 (E597) polyclonal antibody detects endogenous levels of RREB1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 560-610 of Human RREB1.
MW: ~ 181 kDa
Swis Prot.: Q92766
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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