RRM1 antibody (clone 40000), anti-human
€435.00
In stock
SKU
AC-AT3729a
Catalog Number: AC-AT3729a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT3729a">Request Information
Background:
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Other Names:
Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit, RRM1, RR1
Antigen Type:
Recombinant Protein
Gene Name: RRM1
Gene ID: 6240
NCBI Accession: NP_001024.1
Primary Accession: P23921
Other Accession: NM_001033
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Other Names:
Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit, RRM1, RR1
Antigen Type:
Recombinant Protein
Gene Name: RRM1
Gene ID: 6240
NCBI Accession: NP_001024.1
Primary Accession: P23921
Other Accession: NM_001033
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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