RTKN antibody (clone 200000), anti-human
€435.00
In stock
SKU
AC-AT3733a
Catalog Number: AC-AT3733a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
Request Information AC-AT3733a">Request Information
Background:
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Rhotekin, RTKN (HGNC:10466), RTKN1
Antigen Type:
Recombinant Protein
Gene Name: RTKN (HGNC:10466)
Gene ID: 6242
NCBI Accession: NP_001015055.1;NP_001015056.1;NP_149035.1
Primary Accession: Q9BST9
Other Accession: NM_033046
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Rhotekin, RTKN (HGNC:10466), RTKN1
Antigen Type:
Recombinant Protein
Gene Name: RTKN (HGNC:10466)
Gene ID: 6242
NCBI Accession: NP_001015055.1;NP_001015056.1;NP_149035.1
Primary Accession: Q9BST9
Other Accession: NM_033046
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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