Rtn-3 monoclonal antibody, anti-human
€0.00
In stock
SKU
BT-MCA1110
Catalog Number: BT-MCA1110
Size(s): 50μL, 100μL
Isotype: Mouse IgG
Reactivity: human
Application(s): IF, ICC, ELISA
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG
Reactivity: human
Application(s): IF, ICC, ELISA
Datasheet
Request Information
Background:
This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
Research Area: Cell Biology, Signal Transduction, Metabolism, Cancer
Synonyms: RTN3, ASYIP, NSPL2, Reticulon-3, Neuroendocrine-specific protein-like 2, NSP-like protein 2, Neuroendocrine-specific protein-like II, NSP-like protein II, NSPLII
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
Research Area: Cell Biology, Signal Transduction, Metabolism, Cancer
Synonyms: RTN3, ASYIP, NSPL2, Reticulon-3, Neuroendocrine-specific protein-like 2, NSP-like protein 2, Neuroendocrine-specific protein-like II, NSP-like protein II, NSPLII
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
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