RTN3 (clone 1E11), anti-human

RTN3 (clone 1E11), anti-human

€0.00
In stock
SKU
BT-MCA2524
Catalog Number: BT-MCA2524
Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity: human
Application(s): ICC
Datasheet
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Background:
RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

Research Area: Cell Biology, Signal Transduction, Metabolism, Cancer

Synonyms: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1

Immunogen: Purified recombinant fragment of RTN3 expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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