RUNX1 (clone 2B5), anti-human

RUNX1 (clone 2B5), anti-human

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In stock
SKU
BT-MCA3699
Catalog Number: BT-MCA3699
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB
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Background:
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Research Area: Neuroscience

Synonyms: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, RUNX1

Immunogen: Synthesized peptide of human RUNX1.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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