RUNX3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP14667c
Background:
This gene encodes a member of the runt domain-containingfamily of transcription factors. A heterodimer of this protein anda beta subunit forms a complex that binds to the core DNA sequence5'-PYGPYGGT-3' found in a number of enhancers and promoters, andcan either activate or suppress transcription. It also interactswith other transcription factors. It functions as a tumorsuppressor, and the gene is frequently deleted or transcriptionallysilenced in cancer. Multiple transcript variants encoding differentisoforms have been found for this gene.
Other Names:
Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, RUNX3, AML2, CBFA3, PEBP2A3
Gene Name: RUNX3
Gene ID: 864
Primary Accession: Q13761
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the runt domain-containingfamily of transcription factors. A heterodimer of this protein anda beta subunit forms a complex that binds to the core DNA sequence5'-PYGPYGGT-3' found in a number of enhancers and promoters, andcan either activate or suppress transcription. It also interactswith other transcription factors. It functions as a tumorsuppressor, and the gene is frequently deleted or transcriptionallysilenced in cancer. Multiple transcript variants encoding differentisoforms have been found for this gene.
Other Names:
Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, RUNX3, AML2, CBFA3, PEBP2A3
Gene Name: RUNX3
Gene ID: 864
Primary Accession: Q13761
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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