RXR gamma (clone 1373), anti-human, mouse, rat, bovine, monkey
€510.00
In stock
SKU
253214
Protein Family: Transcription Factors, Receptors and Channels
Pathway and Disease: Cancers, Endocrine System
Description:
Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
Alternate Names: Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma, RXRG
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P48443
Antigen: KLH-conjugated peptide encompassing a sequence within human retinoic X receptor, gamma-isotype.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cancers, Endocrine System
Description:
Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
Alternate Names: Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma, RXRG
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P48443
Antigen: KLH-conjugated peptide encompassing a sequence within human retinoic X receptor, gamma-isotype.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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