S100A6 (clone 7D11), anti-human

Background:
Calcyclin encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Research Area: Cell biology, Epigenetics and nuclear signaling

Synonyms: S100A6, 2A9, PRA, 5B10, CABP, CACY

Immunogen: Purified recombinant fragment of calcyclin expressed in E. Coli.

Formulation: Purified antibody in PBS containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage