S100A7 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60481
Background:
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to the S-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation.S100A7 plays a role in the pathogenesis of inflammatory skin disease,as a chemotactic factor for hematopoietic cells.It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.
Alternative Name:
Protein S100-A7, Psoriasin, S100 calcium-binding protein A7, S100A7, PSOR1, S100A7C
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: S100A7 polyclonal antibody detects endogenous levels of S100A7 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human S100A7.
MW: ~ 11 kDa
Swis Prot.: P31151
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.4.
Storage:
Store at 4°C short term. Aliquot and store at -21°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to the S-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation.S100A7 plays a role in the pathogenesis of inflammatory skin disease,as a chemotactic factor for hematopoietic cells.It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.
Alternative Name:
Protein S100-A7, Psoriasin, S100 calcium-binding protein A7, S100A7, PSOR1, S100A7C
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: S100A7 polyclonal antibody detects endogenous levels of S100A7 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human S100A7.
MW: ~ 11 kDa
Swis Prot.: P31151
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.4.
Storage:
Store at 4°C short term. Aliquot and store at -21°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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