S100B monoclonal, anti-mouse
€0.00
In stock
SKU
AC-AM1942b
Catalog Number: AC-AM1942b
Size: 80 µl, 400 µl
Isotype: mouse IgM,k
Clone Name: 271CT14.3.3
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgM,k
Clone Name: 271CT14.3.3
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Other Names:
Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100B
Target/Specificity:
This S100B monoclonal antibody is generated from mouse immunized with S100B recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: S100B {ECO:0000303|PubMed:6487634, ECO:0000312|HGNC:HGNC:10500}
Gene ID: 6285
Primary Accession: P04271
NCBI Accession: NP_006263.1
Other Accession: Q6YNR6; NP_006263.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Other Names:
Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100B
Target/Specificity:
This S100B monoclonal antibody is generated from mouse immunized with S100B recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: S100B {ECO:0000303|PubMed:6487634, ECO:0000312|HGNC:HGNC:10500}
Gene ID: 6285
Primary Accession: P04271
NCBI Accession: NP_006263.1
Other Accession: Q6YNR6; NP_006263.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
| Is Featured? | No |
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