S100B/S100 Beta monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO13602
Catalog Number: AC-ABO13602
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, IP
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, IP
Datasheet
Request Information
Description: Anti-S100B/S100 Beta Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity..
Other Names: Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100B {ECO:0000303|PubMed:6487634, ECO:0000312|HGNC:HGNC:10500}
Clone Name(s):
Clone: BCB-19
Subcellular Localization: Cytoplasm. Nucleus.
Tissue Specificity: Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
Gene ID: 6285
Immunogen: A synthesized peptide derived from human S100B
Calculated MW: 10713
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity..
Other Names: Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100B {ECO:0000303|PubMed:6487634, ECO:0000312|HGNC:HGNC:10500}
Clone Name(s):
Clone: BCB-19
Subcellular Localization: Cytoplasm. Nucleus.
Tissue Specificity: Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
Gene ID: 6285
Immunogen: A synthesized peptide derived from human S100B
Calculated MW: 10713
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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