S1P1 (clone 2B9), anti-human antibody
€360.00
In stock
SKU
AC-ABV12027-50
Catalog Number: AC-ABV12027-50
Size: 50 µg
Host: Mouse IgG
Applications: WB, IF, E, IP
Datasheet
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Size: 50 µg
Host: Mouse IgG
Applications: WB, IF, E, IP
Datasheet
Request Information
Background:
Sphingosine 1-Phosphate Receptor 1 (S1P1) is a multi-pass cell membrane protein that belongs to the Gprotein coupled receptor superfamily (GPCR). S1P1 is a receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Clinical significance of S1P1 encompasses various diseases including cancer and multiple sclerosis. S1P1 seems to be coupled to the G(i/o) subclass of heteromeric G proteins
Other Names:
S1P Receptor 1, S1PR1, Sphingosine 1-Phosphate Receptor 1, Endothelial differentiation GProtein Coupled Receptor 1, EDG-1.
Primary Accession: P21453
Gene Name: S1PR1
Gene ID: 1901
Sphingosine 1-Phosphate Receptor 1 (S1P1) is a multi-pass cell membrane protein that belongs to the Gprotein coupled receptor superfamily (GPCR). S1P1 is a receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Clinical significance of S1P1 encompasses various diseases including cancer and multiple sclerosis. S1P1 seems to be coupled to the G(i/o) subclass of heteromeric G proteins
Other Names:
S1P Receptor 1, S1PR1, Sphingosine 1-Phosphate Receptor 1, Endothelial differentiation GProtein Coupled Receptor 1, EDG-1.
Primary Accession: P21453
Gene Name: S1PR1
Gene ID: 1901
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