S6 Kinase Substrate [229-239] Peptide

Protein Family: Protein Kinases, Ribosomes

Pathway and Disease: Endocrine System, Signal Transduction, Translation

Alternate Names: 40S ribosomal protein S6; phosphoprotein NP33; RPS6

Accession No.: P62753

Description:
Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents and mitogens and the dephosphorylation by growth arrest. The 229-239 peptide contain two phosphorylation sites, Ser235 and Ser236.

Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

MW: 1313.58 g/mol

Sequence:
Human: H-Ala-Lys-Arg-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-OH or H-AKRRRLSSLRA-OH

Composition:
C54H104N24O14

Purity:
> 95% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.