SAFB antibody (clone 5A11), anti-human
€435.00
In stock
SKU
AC-AT3767a
Catalog Number: AC-AT3767a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT3767a">Request Information
Background:
This gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.
Other Names:
Scaffold attachment factor B1, SAF-B, SAF-B1, HSP27 estrogen response element-TATA box-binding protein, HSP27 ERE-TATA-binding protein, SAFB, HAP, HET, SAFB1
Antigen Type:
Recombinant Protein
Gene Name: SAFB
Gene ID: 6294
NCBI Accession: NP_001188267.1;NP_001188268.1;NP_001188269.1;NP_002958.2
Primary Accession: Q15424
Other Accession: NM_002967
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.
Other Names:
Scaffold attachment factor B1, SAF-B, SAF-B1, HSP27 estrogen response element-TATA box-binding protein, HSP27 ERE-TATA-binding protein, SAFB, HAP, HET, SAFB1
Antigen Type:
Recombinant Protein
Gene Name: SAFB
Gene ID: 6294
NCBI Accession: NP_001188267.1;NP_001188268.1;NP_001188269.1;NP_002958.2
Primary Accession: Q15424
Other Accession: NM_002967
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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