SAFB Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP17362a
Background:
This gene encodes a DNA-binding protein that has highspecificity for scaffold or matrix attachment region DNA elements(S/MAR DNA). This protein is thought to be involved in attachingthe base of chromatin loops to the nuclear matrix but there isconflicting evidence as to whether this protein is a component ofchromatin or a nuclear matrix protein. Scaffold attachment factorsare a specific subset of nuclear matrix proteins (NMP) thatspecifically bind to S/MAR. This encoded protein is thought toserve as a molecular base to assemble a 'transcriptosome complex'in the vicinity of actively transcribed genes. It is involved inthe regulation of the heat shock protein 27 transcription and alsocan act as an estrogen receptor corepressor. This gene is acandidate gene for breast tumorigenesis.
Other Names:
Scaffold attachment factor B1, SAF-B, SAF-B1, HSP27 estrogen response element-TATA box-binding protein, HSP27 ERE-TATA-binding protein, SAFB, HAP, HET, SAFB1
Gene Name: SAFB
Gene ID: 6294
Primary Accession: Q15424
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a DNA-binding protein that has highspecificity for scaffold or matrix attachment region DNA elements(S/MAR DNA). This protein is thought to be involved in attachingthe base of chromatin loops to the nuclear matrix but there isconflicting evidence as to whether this protein is a component ofchromatin or a nuclear matrix protein. Scaffold attachment factorsare a specific subset of nuclear matrix proteins (NMP) thatspecifically bind to S/MAR. This encoded protein is thought toserve as a molecular base to assemble a 'transcriptosome complex'in the vicinity of actively transcribed genes. It is involved inthe regulation of the heat shock protein 27 transcription and alsocan act as an estrogen receptor corepressor. This gene is acandidate gene for breast tumorigenesis.
Other Names:
Scaffold attachment factor B1, SAF-B, SAF-B1, HSP27 estrogen response element-TATA box-binding protein, HSP27 ERE-TATA-binding protein, SAFB, HAP, HET, SAFB1
Gene Name: SAFB
Gene ID: 6294
Primary Accession: Q15424
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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